Renin-Angiotensin-Aldosterone System Inhibition Increases Podocyte Derivation from Cells of Renin Lineage

Because adult podocytes cannot proliferate and are therefore unable to self-renew, replacement of these cells depends on stem/progenitor cells. Although podocyte number is higher after renin-angiotensin-aldosterone system (RAAS) inhibition in glomerular diseases, the events explaining this increase...

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Bibliographic Details
Published in:J Am Soc Nephrol
Main Authors: Lichtnekert, Julia, Kaverina, Natalya V., Eng, Diana G., Gross, Kenneth W., Kutz, J. Nathan, Pippin, Jeffrey W., Shankland, Stuart J.
Format: Artigo
Language:Inglês
Published: American Society of Nephrology 2016
Subjects:
Basic Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118476/
https://ncbi.nlm.nih.gov/pubmed/27080979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015080877
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