KLF2-mediated disruption of PPAR-γ signaling in lymphatic endothelial cells exposed to chronically increased pulmonary lymph flow

Lymphatic abnormalities associated with congenital heart disease are well described, yet the underlying mechanisms remain poorly understood. Using a clinically relevant ovine model of congenital heart disease with increased pulmonary blood flow, we have previously demonstrated that lymphatic endothe...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Morris, Catherine J., Kameny, Rebecca J., Boehme, Jason, Gong, Wenhui, He, Youping, Zhu, Terry, Maltepe, Emin, Raff, Gary W., Fineman, Jeffrey R., Datar, Sanjeev A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6087778/
https://ncbi.nlm.nih.gov/pubmed/29631374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00635.2017
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