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Synthesis and antitumor activity of bis(hydroxymethyl)propionate analogs of pterostilbene in cisplatin-resistant human oral cancer cells

The aim of this study was to develop a new drug substance with low toxicity and effective inhibitory activity against cisplatin-resistant oral cancer. The naturally produced pterostilbene was selected as the lead compound for design and synthesis of a series of bis(hydroxymethyl)propionate-based pro...

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Détails bibliographiques
Publié dans:Bioorg Med Chem
Auteurs principaux: Hsieh, Min-Tsang, Huang, Li-Jiau, Wu, Tian-Shung, Lin, Hui-Yi, Morris-Natschke, Susan L., Lee, Kuo-Hsiung, Kuo, Sheng-Chu
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6087491/
https://ncbi.nlm.nih.gov/pubmed/29908756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2018.06.011
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