A Single-Cell Transcriptome Atlas of the Aging Drosophila Brain

The diversity of cell types and regulatory states in the brain, and how these change during aging, remains largely unknown. We present a single-cell transcriptome atlas of the entire adult Drosophila melanogaster brain sampled across its lifespan. Cell clustering identified 87 initial cell clusters...

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Publicat a:Cell
Autors principals: Davie, Kristofer, Janssens, Jasper, Koldere, Duygu, De Waegeneer, Maxime, Pech, Uli, Kreft, Łukasz, Aibar, Sara, Makhzami, Samira, Christiaens, Valerie, Bravo González-Blas, Carmen, Poovathingal, Suresh, Hulselmans, Gert, Spanier, Katina I., Moerman, Thomas, Vanspauwen, Bram, Geurs, Sarah, Voet, Thierry, Lammertyn, Jeroen, Thienpont, Bernard, Liu, Sha, Konstantinides, Nikos, Fiers, Mark, Verstreken, Patrik, Aerts, Stein
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6086935/
https://ncbi.nlm.nih.gov/pubmed/29909982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.05.057
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