The transcription factor Grainyhead primes epithelial enhancers for spatiotemporal activation by displacing nucleosomes

Transcriptional enhancers function as docking platforms for combinations of transcription factors to control gene expression. How enhancer sequences determine nucleosome occupancy, transcription factor recruitment, and transcriptional activation in vivo remains unclear. Using ATAC-seq across a panel...

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Detalhes bibliográficos
Publicado no:Nat Genet
Main Authors: Jacobs, Jelle, Atkins, Mardelle, Davie, Kristofer, Imrichova, Hana, Romanelli, Lucia, Christiaens, Valerie, Hulselmans, Gert, Potier, Delphine, Wouters, Jasper, Taskiran, Ibrahim Ihsan, Paciello, Giulia, González-Blas, Carmen Bravo, Koldere, Duygu, Aibar, Sara, Halder, Georg, Aerts, Stein
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031307/
https://ncbi.nlm.nih.gov/pubmed/29867222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-018-0140-x
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