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cisTopic: cis-Regulatory topic modelling on single-cell ATAC-seq data
We present cisTopic, a probabilistic framework to simultaneously discover co-accessible enhancers and stable cell states from sparse single-cell epigenomics data (http://github.com/aertslab/cistopic). On a compendium of single-cell ATAC-seq datasets from differentiating hematopoietic cells, brain, a...
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| Publicado no: | Nat Methods |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6517279/ https://ncbi.nlm.nih.gov/pubmed/30962623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-019-0367-1 |
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