cGMP-dependent Protein Kinase-2 Regulates Bone Mass and Prevents Diabetic Bone Loss

NO/cGMP signaling is important for bone remodeling in response to mechanical and hormonal stimuli, but the downstream mediator(s) regulating skeletal homeostasis are incompletely defined. We generated transgenic mice expressing a partly-activated, mutant cGMP-dependent protein kinase type 2 (PKG2(R2...

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Detalhes bibliográficos
Publicado no:J Endocrinol
Main Authors: Ramdani, Ghania, Schall, Nadine, Kalyanaraman, Hema, Wahwah, Nisreen, Moheize, Sahar, Lee, Jenna J., Sah, Robert L., Pfeifer, Alexander, Casteel, Darren E., Pilz, Renate B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6086127/
https://ncbi.nlm.nih.gov/pubmed/29914933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-18-0286
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