A NOVEL, DIRECT NO DONOR REGULATES OSTEOBLAST AND OSTEOCLAST FUNCTIONS AND INCREASES BONE MASS IN OVARIECTOMIZED MICE

Most FDA-approved treatments for osteoporosis target osteoclastic bone resorption. Only PTH derivatives improve bone formation, but they have drawbacks, and novel bone-anabolic agents are needed. Nitrates, which generate NO, improved BMD in estrogen-deficient rats and may improve bone formation mark...

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Detalhes bibliográficos
Publicado no:J Bone Miner Res
Main Authors: Kalyanaraman, Hema, Ramdani, Ghania, Joshua, Jisha, Schall, Nadine, Boss, Gerry R., Cory, Esther, Sah, Robert L., Casteel, Darren E., Pilz, Renate B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5199609/
https://ncbi.nlm.nih.gov/pubmed/27391172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2909
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