Th1-polarizing immunization with egg antigens correlates with severe exacerbation of immunopathology and death in schistosome infection
In schistosomiasis mansoni, parasite eggs precipitate an intrahepatic granulomatous and fibrosing inflammatory process, which is mediated by, and dependent on, MHC class II-restricted CD4 T helper (Th) lymphocytes specific for schistosome egg antigens (SEA). In the mouse model of the disease, CBA mi...
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| Yayımlandı: | Proc Natl Acad Sci U S A |
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| Asıl Yazarlar: | , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
National Academy of Sciences
2001
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC60855/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11606762/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.231258498 |
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