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IL-15 Induces Alloreactive CD28(−) Memory CD8 T Cell Proliferation and CTLA4-Ig Resistant Memory CD8 T Cell Activation
The presence of CD28(−) memory CD8 T cells in the peripheral blood of renal transplant patients is a risk factor for graft rejection and resistance to CTLA-4Ig induction therapy. In vitro analyses have indicated poor alloantigen-induced CD28(−) memory CD8 T cell proliferation, raising questions abou...
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| Pubblicato in: | Am J Transplant |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6083870/ https://ncbi.nlm.nih.gov/pubmed/24842641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.12719 |
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