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Peri-Transplant VLA-4 Blockade Inhibits Endogenous Memory CD8 T Cell Infiltration into High Risk Cardiac Allografts and CTLA-4Ig Resistant Rejection
Recipient endogenous memory CD8 T cells expressing reactivity to donor class I MHC infiltrate MHC-mismatched cardiac allografts within 24 hours after reperfusion and express effector functions mediating graft injury. The current study tested the efficacy of VLA-4 blockade to inhibit endogenous memor...
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| Publicado no: | Am J Transplant |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6433496/ https://ncbi.nlm.nih.gov/pubmed/30372587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.15147 |
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