Interleukin (IL)-1 Receptor Signaling on Graft Parenchymal Cells Regulates Memory and De Novo Donor-Reactive CD8 T Cell Responses to Cardiac Allografts

Reperfusion of organ allografts induces a potent inflammatory response that directs rapid memory T cell, neutrophil and macrophage graft infiltration and their activation to express functions mediating graft tissue injury. The role of cardiac allograft IL-1 receptor signaling in this early inflammat...

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Bibliographic Details
Published in:J Immunol
Main Authors: Iida, Shoichi, Tsuda, Hidetoshi, Tanaka, Toshiaki, Kish, Danielle D., Abe, Toyofumi, Su, Charles A., Abe, Ryo, Tanabe, Kazunari, Valujskikh, Anna, Baldwin, William M., Fairchild, Robert L.
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4779689/
https://ncbi.nlm.nih.gov/pubmed/26856697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500876
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