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Transient Lymphopenia Breaks Costimulatory Blockade-Based Peripheral Tolerance and Initiates Cardiac Allograft Rejection

Lymphopenia is induced by lymphoablative therapies and chronic viral infections. We assessed the impact of lymphopenia on cardiac allograft survival in recipients conditioned with peri-transplant costimulatory blockade (CB) to promote long-term graft acceptance. After vascularized MHC-mismatched het...

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Bibliografiske detaljer
Main Authors: Iida, Shoichi, Suzuki, Toshihiro, Tanabe, Kazunari, Valujskikh, Anna, Fairchild, Robert L., Abe, Ryo
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4216721/
https://ncbi.nlm.nih.gov/pubmed/23834725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.12342
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