Regional Distribution of CNS Antigens Differentially Determines T-Cell Mediated Neuroinflammation in a CX3CR1-Dependent Manner

T cells continuously sample CNS-derived antigens in the periphery, yet it is unknown how they sample and respond to CNS antigens derived from distinct brain areas. We expressed ovalbumin (OVA) neoepitopes in regionally distinct CNS areas (Cnp-OVA and Nes-OVA mice) to test peripheral antigen sampling...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Neurosci
Egile Nagusiak: Rayasam, Aditya, Kijak, Julie A., Dallmann, McKenna, Hsu, Martin, Zindl, Nicole, Lindstedt, Anders, Steinmetz, Leah, Harding, Jeffrey S., Harris, Melissa G., Karman, Jozsef, Sandor, Matyas, Fabry, Zsuzsanna
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Society for Neuroscience 2018
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6083460/
https://ncbi.nlm.nih.gov/pubmed/29959236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0366-18.2018
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