Blocking Ca(2+) Channel β(3) Subunit Reverses Diabetes

Voltage-gated Ca(2+) channels (Ca(v)) are essential for pancreatic beta cell function as they mediate Ca(2+) influx, which leads to insulin exocytosis. The β3 subunit of Ca(v) (Ca(v)β(3)) has been suggested to regulate cytosolic Ca(2+) ([Ca(2+)](i)) oscillation frequency and insulin secretion under...

Full description

Saved in:
Bibliographic Details
Published in:Cell Rep
Main Authors: Lee, Kayoung, Kim, Jaeyoon, Köhler, Martin, Yu, Jia, Shi, Yue, Yang, Shao-Nian, Ryu, Sung Ho, Berggren, Per-Olof
Format: Artigo
Language:Inglês
Published: Cell Press 2018
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6083041/
https://ncbi.nlm.nih.gov/pubmed/30044988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.06.086
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items