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Blocking Ca(2+) Channel β(3) Subunit Reverses Diabetes
Voltage-gated Ca(2+) channels (Ca(v)) are essential for pancreatic beta cell function as they mediate Ca(2+) influx, which leads to insulin exocytosis. The β3 subunit of Ca(v) (Ca(v)β(3)) has been suggested to regulate cytosolic Ca(2+) ([Ca(2+)](i)) oscillation frequency and insulin secretion under...
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| Publicat a: | Cell Rep |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cell Press
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6083041/ https://ncbi.nlm.nih.gov/pubmed/30044988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.06.086 |
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