Transcriptional and physiological adaptations in nucleus accumbens somatostatin interneurons that regulate behavioral responses to cocaine

The role of somatostatin interneurons in nucleus accumbens (NAc), a key brain reward region, remains poorly understood due to the fact that these cells account for < 1% of NAc neurons. Here, we use optogenetics, electrophysiology, and RNA-sequencing to characterize the transcriptome and functioni...

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Publié dans:Nat Commun
Auteurs principaux: Ribeiro, Efrain A., Salery, Marine, Scarpa, Joseph R., Calipari, Erin S., Hamilton, Peter J., Ku, Stacy M., Kronman, Hope, Purushothaman, Immanuel, Juarez, Barbara, Heshmati, Mitra, Doyle, Marie, Lardner, Casey, Burek, Dominicka, Strat, Ana, Pirpinias, Stephen, Mouzon, Ezekiell, Han, Ming-Hu, Neve, Rachael L., Bagot, Rosemary C., Kasarskis, Andrew, Koo, Ja Wook, Nestler, Eric J.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6082848/
https://ncbi.nlm.nih.gov/pubmed/30089879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05657-9
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