Dopaminergic regulation of nucleus accumbens cholinergic interneurons demarcates susceptibility to cocaine addiction

BACKGROUND: Cholinergic interneurons (ChINs) in the nucleus accumbens (NAc) play critical roles in processing information related to reward. However, the contribution of ChINs to emergence of addiction-like behaviors and its underlying molecular mechanisms remain elusive. METHODS: We employed cocain...

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Gepubliceerd in:Biol Psychiatry
Hoofdauteurs: Lee, Joo Han, Ribeiro, Efrain A, Kim, Jeongseop, Ko, Bumjin, Kronman, Hope, Jeong, Yun Ha, Kim, Jong Kyoung, Janak, Patricia H, Nestler, Eric J, Koo, Ja Wook, Kim, Joung-Hun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7584775/
https://ncbi.nlm.nih.gov/pubmed/32622465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2020.05.003
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