Transcriptional and physiological adaptations in nucleus accumbens somatostatin interneurons that regulate behavioral responses to cocaine

The role of somatostatin interneurons in nucleus accumbens (NAc), a key brain reward region, remains poorly understood due to the fact that these cells account for < 1% of NAc neurons. Here, we use optogenetics, electrophysiology, and RNA-sequencing to characterize the transcriptome and functioni...

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Vydáno v:Nat Commun
Hlavní autoři: Ribeiro, Efrain A., Salery, Marine, Scarpa, Joseph R., Calipari, Erin S., Hamilton, Peter J., Ku, Stacy M., Kronman, Hope, Purushothaman, Immanuel, Juarez, Barbara, Heshmati, Mitra, Doyle, Marie, Lardner, Casey, Burek, Dominicka, Strat, Ana, Pirpinias, Stephen, Mouzon, Ezekiell, Han, Ming-Hu, Neve, Rachael L., Bagot, Rosemary C., Kasarskis, Andrew, Koo, Ja Wook, Nestler, Eric J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6082848/
https://ncbi.nlm.nih.gov/pubmed/30089879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05657-9
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