Tet1 in Nucleus Accumbens Opposes Depression- and Anxiety-Like Behaviors

Depression is a leading cause of disease burden, yet current therapies fully treat <50% of affected individuals. Increasing evidence implicates epigenetic mechanisms in depression and antidepressant action. Here we examined a possible role for the DNA dioxygenase, ten-eleven translocation protein...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neuropsychopharmacology
Prif Awduron: Feng, Jian, Pena, Catherine J, Purushothaman, Immanuel, Engmann, Olivia, Walker, Deena, Brown, Amber N, Issler, Orna, Doyle, Marie, Harrigan, Eileen, Mouzon, Ezekiell, Vialou, Vincent, Shen, Li, Dawlaty, Meelad M, Jaenisch, Rudolf, Nestler, Eric J
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2017
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5518912/
https://ncbi.nlm.nih.gov/pubmed/28074830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2017.6
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