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Tousled-like kinases stabilize replication forks and show synthetic lethality with checkpoint and PARP inhibitors
DNA sequence and epigenetic information embedded in chromatin must be faithfully duplicated and transmitted to daughter cells during cell division. However, how chromatin assembly and DNA replication are integrated remains unclear. We examined the contribution of the Tousled-like kinases 1 and 2 (TL...
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| Publicat a: | Sci Adv |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Association for the Advancement of Science
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6082654/ https://ncbi.nlm.nih.gov/pubmed/30101194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aat4985 |
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