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Molecular basis of Tousled-Like Kinase 2 activation

Tousled-like kinases (TLKs) are required for genome stability and normal development in numerous organisms and have been implicated in breast cancer and intellectual disability. In humans, the similar TLK1 and TLK2 interact with each other and TLK activity enhances ASF1 histone binding and is inhibi...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Mortuza, Gulnahar B., Hermida, Dario, Pedersen, Anna-Kathrine, Segura-Bayona, Sandra, López-Méndez, Blanca, Redondo, Pilar, Rüther, Patrick, Pozdnyakova, Irina, Garrote, Ana M., Muñoz, Inés G., Villamor-Payà, Marina, Jauset, Cristina, Olsen, Jesper V., Stracker, Travis H., Montoya, Guillermo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6023931/
https://ncbi.nlm.nih.gov/pubmed/29955062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04941-y
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