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Tranexamic acid for significant traumatic brain injury (The CRASH-3 trial): Statistical analysis plan for an international, randomised, double-blind, placebo-controlled trial

Background: Worldwide, traumatic brain injury (TBI) kills or hospitalises over 10 million people each year. Early intracranial bleeding is common after TBI, increasing the risk of death and disability. Tranexamic acid reduces blood loss in surgery and death due to bleeding in trauma patients with ex...

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Détails bibliographiques
Publié dans:Wellcome Open Res
Auteurs principaux: Roberts, Ian, Belli, Antonio, Brenner, Amy, Chaudhri, Rizwana, Fawole, Bukola, Harris, Tim, Jooma, Rashid, Mahmood, Abda, Shokunbi, Temitayo, Shakur, Haleema
Format: Artigo
Langue:Inglês
Publié: F1000 Research Limited 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6081978/
https://ncbi.nlm.nih.gov/pubmed/30175246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/wellcomeopenres.14700.2
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