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Tranexamic acid for significant traumatic brain injury (The CRASH-3 trial): Statistical analysis plan for an international, randomised, double-blind, placebo-controlled trial

Background: Worldwide, traumatic brain injury (TBI) kills or hospitalises over 10 million people each year. Early intracranial bleeding is common after TBI, increasing the risk of death and disability. Tranexamic acid reduces blood loss in surgery and death due to bleeding in trauma patients with ex...

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Detalhes bibliográficos
Publicado no:Wellcome Open Res
Main Authors: Roberts, Ian, Belli, Antonio, Brenner, Amy, Chaudhri, Rizwana, Fawole, Bukola, Harris, Tim, Jooma, Rashid, Mahmood, Abda, Shokunbi, Temitayo, Shakur, Haleema
Formato: Artigo
Idioma:Inglês
Publicado em: F1000 Research Limited 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6081978/
https://ncbi.nlm.nih.gov/pubmed/30175246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/wellcomeopenres.14700.2
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