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A nested mechanistic sub-study into the effect of tranexamic acid versus placebo on intracranial haemorrhage and cerebral ischaemia in isolated traumatic brain injury: study protocol for a randomised controlled trial (CRASH-3 Trial Intracranial Bleeding Mechanistic Sub-Study [CRASH-3 IBMS])

BACKGROUND: Tranexamic acid prevents blood clots from breaking down and reduces bleeding. However, it is uncertain whether tranexamic acid is effective in traumatic brain injury. The CRASH-3 trial is a randomised controlled trial that will examine the effect of tranexamic acid (versus placebo) on de...

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Dades bibliogràfiques
Publicat a:Trials
Autors principals: Mahmood, Abda, Roberts, Ian, Shakur, Haleema
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5513059/
https://ncbi.nlm.nih.gov/pubmed/28716153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-017-2073-6
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