Effect of tranexamic acid on intracranial haemorrhage and infarction in patients with traumatic brain injury: a pre-planned substudy in a sample of CRASH-3 trial patients

BACKGROUND: Early tranexamic acid (TXA) treatment reduces head injury deaths after traumatic brain injury (TBI). We used brain scans that were acquired as part of the routine clinical practice during the CRASH-3 trial (before unblinding) to examine the mechanism of action of TXA in TBI. Specifically...

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Bibliografiske detaljer
Udgivet i:Emerg Med J
Main Authors: Mahmood, Abda, Needham, Kelly, Shakur-Still, Haleema, Harris, Tim, Jamaluddin, Sabariah Faizah, Davies, David, Belli, Antonio, Mohamed, Fatahul Laham, Leech, Caroline, Lotfi, Hamzah Mohd, Moss, Phil, Lecky, Fiona, Hopkins, Philip, Wong, Darin, Boyle, Adrian, Wilson, Mark, Darwent, Melanie, Roberts, Ian
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Publishing Group 2021
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Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7982942/
https://ncbi.nlm.nih.gov/pubmed/33262252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/emermed-2020-210424
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