Duplex signaling by CaM and Stac3 enhances Ca(V)1.1 function and provides insights into congenital myopathy

Ca(V)1.1 is essential for skeletal muscle excitation–contraction coupling. Its functional expression is tuned by numerous regulatory proteins, yet underlying modulatory mechanisms remain ambiguous as Ca(V)1.1 fails to function in heterologous systems. In this study, by dissecting channel trafficking...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Gen Physiol
Egile Nagusiak: Niu, Jacqueline, Yang, Wanjun, Yue, David T., Inoue, Takanari, Ben-Johny, Manu
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Rockefeller University Press 2018
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6080896/
https://ncbi.nlm.nih.gov/pubmed/29950399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201812005
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