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DNA-Encoded Chemical Libraries: A Selection System Based On Endowing Organic Compounds With Amplifiable Information
The discovery of organic ligands that bind specifically to proteins is a central problem in chemistry, biology and biomedical sciences. The encoding of individual organic molecules with distinctive DNA tags, serving as amplifiable identification barcodes, allows the construction and screening of com...
Αποθηκεύτηκε σε:
Τόπος έκδοσης: | Annu Rev Biochem |
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Κύριοι συγγραφείς: | , |
Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
2018
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6080696/ https://ncbi.nlm.nih.gov/pubmed/29328784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-biochem-062917-012550 |
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