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Novel selection methods for DNA-encoded chemical libraries

Driven by the need for new compounds to serve as biological probes and leads for therapeutic development and the growing accessibility of DNA technologies including high-throughput sequencing, many academic and industrial groups have begun to use DNA-encoded chemical libraries as a source of bioacti...

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Veröffentlicht in:Curr Opin Chem Biol
Hauptverfasser: Chan, Alix I., McGregor, Lynn M., Liu, David R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4475454/
https://ncbi.nlm.nih.gov/pubmed/25723146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2015.02.010
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