PAI1 blocks NMDA receptor-mediated effects of tissue-type plasminogen activator on cell signaling and physiology

The fibrinolysis proteinase tissue-type plasminogen activator (tPA, also known as PLAT) triggers cell signaling and regulates cell physiology. In PC12 cells, Schwann cells and macrophages, the N-methyl-D-aspartate receptor (NMDA-R) mediates tPA signaling. Plasminogen activator inhibitor-1 (PAI1, als...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Cell Sci
Main Authors: Gonias, Steven L., Banki, Michael A., Gilder, Andrew S., Azmoon, Pardis, Campana, Wendy M., Mantuano, Elisabetta
Format: Artigo
Jezik:Inglês
Izdano: The Company of Biologists Ltd 2018
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6080607/
https://ncbi.nlm.nih.gov/pubmed/29930084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.217083
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