Detection and localization of surgically resectable cancers with a multi-analyte blood test

Earlier detection is key to reducing cancer deaths. Here, we describe a blood test that can detect eight common cancer types through assessment of the levels of circulating proteins and mutations in cell-free DNA. We applied this test, called CancerSEEK, to 1005 patients with nonmetastatic, clinical...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Cohen, Joshua D., Li, Lu, Wang, Yuxuan, Thoburn, Christopher, Afsari, Bahman, Danilova, Ludmila, Douville, Christopher, Javed, Ammar A., Wong, Fay, Mattox, Austin, Hruban, Ralph. H., Wolfgang, Christopher L., Goggins, Michael G., Molin, Marco Dal, Wang, Tian-Li, Roden, Richard, Klein, Alison P., Ptak, Janine, Dobbyn, Lisa, Schaefer, Joy, Silliman, Natalie, Popoli, Maria, Vogelstein, Joshua T., Browne, James D., Schoen, Robert E., Brand, Randall E., Tie, Jeanne, Gibbs, Peter, Wong, Hui-Li, Mansfield, Aaron S., Jen, Jin, Hanash, Samir M., Falconi, Massimo, Allen, Peter J., Zhou, Shibin, Bettegowda, Chetan, Diaz, Luis A., Tomasetti, Cristian, Kinzler, Kenneth W., Vogelstein, Bert, Lennon, Anne Marie, Papadopoulos, Nickolas
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6080308/
https://ncbi.nlm.nih.gov/pubmed/29348365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aar3247
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