Detection of aneuploidy in patients with cancer through amplification of long interspersed nucleotide elements (LINEs)

Aneuploidy is a feature of most cancer cells, and a myriad of approaches have been developed to detect it in clinical samples. We previously described primers that could be used to amplify ∼38,000 unique long interspersed nucleotide elements (LINEs) from throughout the genome. Here we have developed...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Douville, Christopher, Springer, Simeon, Kinde, Isaac, Cohen, Joshua D., Hruban, Ralph H., Lennon, Anne Marie, Papadopoulos, Nickolas, Kinzler, Kenneth W., Vogelstein, Bert, Karchin, Rachel
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828610/
https://ncbi.nlm.nih.gov/pubmed/29432176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1717846115
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