Combined Ectopic Expression of Homologous Recombination Factors Promotes Embryonic Stem Cell Differentiation

Homologous recombination (HR), which ensures accurate DNA replication and strand-break repair, is necessary to preserve embryonic stem cell (ESC) self-renewal. However, little is known about how HR factors modulate ESC differentiation and replication stress-associated DNA breaks caused by unique cel...

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Bibliografiske detaljer
Udgivet i:Mol Ther
Main Authors: Choi, Eui-Hwan, Yoon, Seobin, Kim, Keun P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Gene & Cell Therapy 2018
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6079475/
https://ncbi.nlm.nih.gov/pubmed/29503196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.02.003
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