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Combined Ectopic Expression of Homologous Recombination Factors Promotes Embryonic Stem Cell Differentiation
Homologous recombination (HR), which ensures accurate DNA replication and strand-break repair, is necessary to preserve embryonic stem cell (ESC) self-renewal. However, little is known about how HR factors modulate ESC differentiation and replication stress-associated DNA breaks caused by unique cel...
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| Pubblicato in: | Mol Ther |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society of Gene & Cell Therapy
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6079475/ https://ncbi.nlm.nih.gov/pubmed/29503196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.02.003 |
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