Investigating the Mechanism of Action of Diketopiperazines Inhibitors of the Burkholderia cenocepacia Quorum Sensing Synthase CepI: A Site-Directed Mutagenesis Study

Quorum sensing (QS) is a bacterial intercellular communication process which controls the production of major virulence factors, such as proteases, siderophores, and toxins, as well as biofilm formation. Since the inhibition of this pathway reduces bacterial virulence, QS is considered a valuable ca...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Front Pharmacol
Päätekijät: Buroni, Silvia, Scoffone, Viola C., Fumagalli, Marco, Makarov, Vadim, Cagnone, Maddalena, Trespidi, Gabriele, De Rossi, Edda, Forneris, Federico, Riccardi, Giovanna, Chiarelli, Laurent R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2018
Aiheet:
Pharmacology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6079302/
https://ncbi.nlm.nih.gov/pubmed/30108505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00836
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