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Ectopic overexpression of Kir6.1 in the mouse heart impacts on the life expectancy

We recently reported the reduced ATP-sensitive potassium (K(ATP)) channel activities in the transgenic mouse heart overexpressing the vascular type K(ATP) channel pore-forming subunit (Kir6.1). Although dysfunction of cardiac K(ATP) channel has been nominated as a cause of cardiomyopathy in human, t...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Watanabe, Yasuhiro, Kishimoto, Takashi, Miki, Takashi, Seino, Susumu, Nakaya, Haruaki, Matsumoto, Akio
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6078942/
https://ncbi.nlm.nih.gov/pubmed/30082733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30175-5
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