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Gene targeting approach to clarification of ion channel function: studies of Kir6.x null mice

ATP-sensitive potassium (K(ATP)) channels are present in many tissues, including pancreatic β-cells, heart, skeletal muscle, vascular smooth muscle and brain, in which they couple the cell metabolic state to membrane potential. K(ATP) channels are hetero-octameric proteins composed of the pore-formi...

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Autores principales: Seino, Susumu, Miki, Takashi
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1664767/
https://ncbi.nlm.nih.gov/pubmed/12826653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2003.047175
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