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Role of sarcolemmal ATP-sensitive K(+) channels in the regulation of sinoatrial node automaticity: an evaluation using Kir6.2-deficient mice
The role of cardiac sarcolemmal ATP-sensitive K(+) (K(ATP)) channels in the regulation of sinoatrial node (SAN) automaticity is not well defined. Using mice with homozygous knockout (KO) of the Kir6.2 (a pore-forming subunit of cardiac K(ATP) channel) gene, we investigated the pathophysiological rol...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2536586/ https://ncbi.nlm.nih.gov/pubmed/18420708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.148932 |
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