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Role of sarcolemmal ATP-sensitive K(+) channels in the regulation of sinoatrial node automaticity: an evaluation using Kir6.2-deficient mice

The role of cardiac sarcolemmal ATP-sensitive K(+) (K(ATP)) channels in the regulation of sinoatrial node (SAN) automaticity is not well defined. Using mice with homozygous knockout (KO) of the Kir6.2 (a pore-forming subunit of cardiac K(ATP) channel) gene, we investigated the pathophysiological rol...

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Detalles Bibliográficos
Main Authors: Fukuzaki, Koichi, Sato, Toshiaki, Miki, Takashi, Seino, Susumu, Nakaya, Haruaki
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2536586/
https://ncbi.nlm.nih.gov/pubmed/18420708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.148932
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