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Rare cell detection by single cell RNA sequencing as guided by single molecule RNA FISH

Although single cell RNA sequencing can reliably detect large-scale transcriptional programs, it is unclear whether it accurately captures the behavior of individual genes, especially those that express only in rare cells. Here, we use single molecule RNA FISH as a gold standard to assess tradeoffs...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Syst
Egile Nagusiak: Torre, Eduardo, Dueck, Hannah, Shaffer, Sydney, Gospocic, Janko, Gupte, Rohit, Bonasio, Roberto, Kim, Junhyong, Murray, John, Raj, Arjun
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6078200/
https://ncbi.nlm.nih.gov/pubmed/29454938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2018.01.014
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