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Rare cell detection by single cell RNA sequencing as guided by single molecule RNA FISH
Although single cell RNA sequencing can reliably detect large-scale transcriptional programs, it is unclear whether it accurately captures the behavior of individual genes, especially those that express only in rare cells. Here, we use single molecule RNA FISH as a gold standard to assess tradeoffs...
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| Publicado no: | Cell Syst |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6078200/ https://ncbi.nlm.nih.gov/pubmed/29454938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2018.01.014 |
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