SAVER: Gene expression recovery for single-cell RNA sequencing

In single-cell RNA sequencing (scRNA-seq) studies, only a small fraction of the transcripts present in each cell are sequenced. This leads to unreliable quantification of lowly and moderately expressed genes which hinders downstream analysis. To address this challenge, we introduce SAVER (Single-cel...

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Publicado en:Nat Methods
Main Authors: Huang, Mo, Wang, Jingshu, Torre, Eduardo, Dueck, Hannah, Shaffer, Sydney, Bonasio, Roberto, Murray, John I., Raj, Arjun, Li, Mingyao, Zhang, Nancy R.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030502/
https://ncbi.nlm.nih.gov/pubmed/29941873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-018-0033-z
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