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SCALE: modeling allele-specific gene expression by single-cell RNA sequencing
Allele-specific expression is traditionally studied by bulk RNA sequencing, which measures average expression across cells. Single-cell RNA sequencing allows the comparison of expression distribution between the two alleles of a diploid organism and the characterization of allele-specific bursting....
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| Publicado no: | Genome Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5407026/ https://ncbi.nlm.nih.gov/pubmed/28446220 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1200-8 |
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