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Aspirin binds to PPARα to stimulate hippocampal plasticity and protect memory
Despite its long history, until now, no receptor has been identified for aspirin, one of the most widely used medicines worldwide. Here we report that peroxisome proliferator-activated receptor alpha (PPARα), a nuclear hormone receptor involved in fatty acid metabolism, serves as a receptor of aspir...
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| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6077698/ https://ncbi.nlm.nih.gov/pubmed/30012602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1802021115 |
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