Aspirin binds to PPARα to stimulate hippocampal plasticity and protect memory

Despite its long history, until now, no receptor has been identified for aspirin, one of the most widely used medicines worldwide. Here we report that peroxisome proliferator-activated receptor alpha (PPARα), a nuclear hormone receptor involved in fatty acid metabolism, serves as a receptor of aspir...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Patel, Dhruv, Roy, Avik, Kundu, Madhuchhanda, Jana, Malabendu, Luan, Chi-Hao, Gonzalez, Frank J., Pahan, Kalipada
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2018
Konular:
PNAS Plus
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6077698/
https://ncbi.nlm.nih.gov/pubmed/30012602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1802021115
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