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Harnessing natural DNA modifying activities for editing of the genome and epigenome
The introduction of site-specific DNA modifications to the genome or epigenome presents great opportunities for manipulating biological systems. Such changes are now possible through the combination of DNA-modifying enzymes with targeting modules, including dCas9, that can localize the enzymes to sp...
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| Publicado en: | Curr Opin Chem Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6076857/ https://ncbi.nlm.nih.gov/pubmed/29452938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2018.01.016 |
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