Tet2 Regulates Osteoclast Differentiation by Interacting with Runx1 and Maintaining Genomic 5-Hydroxymethylcytosine (5hmC)

As a dioxygenase, Ten-Eleven Translocation 2 (TET2) catalyzes subsequent steps of 5-methylcytosine (5mC) oxidation. TET2 plays a critical role in the self-renewal, proliferation, and differentiation of hematopoietic stem cells, but its impact on mature hematopoietic cells is not well-characterized....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Genomics Proteomics Bioinformatics
Egile Nagusiak: Chu, Yajing, Zhao, Zhigang, Sant, David Wayne, Zhu, Ganqian, Greenblatt, Sarah M., Liu, Lin, Wang, Jinhuan, Cao, Zeng, Tho, Jeanette Cheng, Chen, Shi, Liu, Xiaochen, Zhang, Peng, Maciejewski, Jaroslaw P., Nimer, Stephen, Wang, Gaofeng, Yuan, Weiping, Yang, Feng-Chun, Xu, Mingjiang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2018
Gaiak:
Original Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6076382/
https://ncbi.nlm.nih.gov/pubmed/29908294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gpb.2018.04.005
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