Tet2 Regulates Osteoclast Differentiation by Interacting with Runx1 and Maintaining Genomic 5-Hydroxymethylcytosine (5hmC)

As a dioxygenase, Ten-Eleven Translocation 2 (TET2) catalyzes subsequent steps of 5-methylcytosine (5mC) oxidation. TET2 plays a critical role in the self-renewal, proliferation, and differentiation of hematopoietic stem cells, but its impact on mature hematopoietic cells is not well-characterized....

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Dades bibliogràfiques
Publicat a:Genomics Proteomics Bioinformatics
Autors principals: Chu, Yajing, Zhao, Zhigang, Sant, David Wayne, Zhu, Ganqian, Greenblatt, Sarah M., Liu, Lin, Wang, Jinhuan, Cao, Zeng, Tho, Jeanette Cheng, Chen, Shi, Liu, Xiaochen, Zhang, Peng, Maciejewski, Jaroslaw P., Nimer, Stephen, Wang, Gaofeng, Yuan, Weiping, Yang, Feng-Chun, Xu, Mingjiang
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2018
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6076382/
https://ncbi.nlm.nih.gov/pubmed/29908294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gpb.2018.04.005
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