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Stable 5-hydroxymethylcytosine (5hmC) acquisition marks gene activation during chondrogenic differentiation

Regulation of gene expression changes during chondrogenic differentiation by DNA methylation and demethylation is little understood. Methylated cytosines (5mC) are oxidized by the ten-eleven-translocation (TET) proteins to 5-hydroxymethylcytosines (5hmC), 5-formylcytosines (5fC) and 5-carboxylcytosi...

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Detalhes bibliográficos
Publicado no:J Bone Miner Res
Main Authors: Taylor, Sarah E. B., Li, Ye Henry, Smeriglio, Piera, Rath, Madhusikta, Wong, Wing H., Bhutani, Nidhi
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860191/
https://ncbi.nlm.nih.gov/pubmed/26363184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2711
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