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Stable 5-hydroxymethylcytosine (5hmC) acquisition marks gene activation during chondrogenic differentiation

Regulation of gene expression changes during chondrogenic differentiation by DNA methylation and demethylation is little understood. Methylated cytosines (5mC) are oxidized by the ten-eleven-translocation (TET) proteins to 5-hydroxymethylcytosines (5hmC), 5-formylcytosines (5fC) and 5-carboxylcytosi...

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Bibliographische Detailangaben
Veröffentlicht in:J Bone Miner Res
Hauptverfasser: Taylor, Sarah E. B., Li, Ye Henry, Smeriglio, Piera, Rath, Madhusikta, Wong, Wing H., Bhutani, Nidhi
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860191/
https://ncbi.nlm.nih.gov/pubmed/26363184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2711
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