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Stable 5-hydroxymethylcytosine (5hmC) acquisition marks gene activation during chondrogenic differentiation

Regulation of gene expression changes during chondrogenic differentiation by DNA methylation and demethylation is little understood. Methylated cytosines (5mC) are oxidized by the ten-eleven-translocation (TET) proteins to 5-hydroxymethylcytosines (5hmC), 5-formylcytosines (5fC) and 5-carboxylcytosi...

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Podrobná bibliografie
Vydáno v:J Bone Miner Res
Hlavní autoři: Taylor, Sarah E. B., Li, Ye Henry, Smeriglio, Piera, Rath, Madhusikta, Wong, Wing H., Bhutani, Nidhi
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860191/
https://ncbi.nlm.nih.gov/pubmed/26363184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2711
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